Several clinical studies conducted at various government and non-government institutions across the country have proven that regular use of Dr. JRK’s 777 Oil provides rapid and prolonged relief from psoriatic lesions.
The therapeutic efficacy of Dr.JRK’s 777 oil has been endorsed by clinicians from both allopathic and traditional Indian systems of medicine for more than 32 years making it a widely trusted and most effective treatment for psoriasis.
In a comparative evaluation with calcipotriol, Dr. JRK’s 777 Oil achieved greater improvement in the PASI* score (91.9%) compared to calcipotriol (90.8%), indicating its strong overall effectiveness in the treatment of psoriasis and in reducing disease severity.
PASI - Psoriasis Area Severity Index
Clinical trial done by at King George Hospital, Visakhapatnam
A clinical trial was conducted on 30 patients with chronic plaque-type psoriasis over a period of 12 weeks.
The observations were based on four criteria
1. Scaling
2. Plaque thickness
3. Itching
4. Erythema
All patients showed a significant reduction in all four parameters, demonstrating the anti-psoriatic efficacy of Dr. JRK’s 777 Oil in the treatment of psoriasis.
JRK’s 777 oil acts upon the impaired keratinocytes butdoes not affect the normal cells – Safe for long term use.
Safety studies were conducted on Dr. JRK’s 777 oil under OECD (Organization for Economic Co-operation and Development) guidelines for Toxicity studies.
| NAME OF THE STUDY | FINDINGS FOR Dr. JRK’s 777 OIL |
|---|---|
| Skin Sensitization in Guinea pig | Did not produce skin sensitization effect after 24 h and 48 h of removal of the patch |
| Effect on Mucus membrane | Did not produce mucus membrane irritation |
| In vitro Mammalian cell gene mutation test - chinese hamster ovary K1 cell line | Did not show any mutagenic effect |
| Bacterial reverse mutation test using S. typhimurium and E.coli WP2 uvr A | Did not show any mutagenic effect on all four strains of S. typhimurium and E.coli |
| Mammalian erythrocyte Micronucleus testing swiss albino mice | Did not produce toxic effect on bone marrow and total polychromatic/erythrocyte ratio (P/E) |
| Acute lethal dose | No change in the viscera/organs and in the histological parameters was observed even in the animals that received high dose of the product |
| Reproduction developmental toxicity screening | Did not produce reproduction and developmental toxicity. Pups did not reveal any abnormalities either at reproductive and histological level |
✔️ Dr. JRK’s 777 Oil inhibits the multiplication of human keratinocyte HaCaT cells, with an IC50 value of 2.8 mg/mL
✔️ The effect of Dr. JRK’s 777 Oil was found to be growth-inhibitory rather than cytotoxic in nature. Hence, Dr. JRK’s 777 Oil is considered safe and effective in controlling the multiplication of HaCaT cells
Dr. JRK’s 777 Oil has been studied for its antioxidant activity, anti-rancidity properties, and anti-glycation effects. Scientific studies have also demonstrated its ability to reduce inflammation.
