Dr. JRK’s 777 oil did not show any cytotoxic effect in fibroblast, whereas rancid coconut oil produced cytotoxicity. The fibroblast toxicity was directly proportional to acid value
According to OECD (Organization for economic co-operation and development) :
Studies include:
- Skin sensitization in Guinea Pig – Dr. JRK’s 777 oil does not cause skin sensitization
- Effect on mucous membrane - Dr. JKR’s 777 oil does not cause mucus membrane irritation
- In vitro mammalian cell gene mutation test (Chinese hamster ovary k1 cell line) – Dr. JRK’s 777 oil does not cause mutagenicity
- Bacterial reverse mutation test using S. typhimurium and E. coli WP2 uvr A – Dr. JRK’s 777 oil does not cause reverse mutation
- Mammalian erythrocyte micronucleus testing swiss albino mice – Dr. JRK’s 777 oil does not cause any toxicity to visceral organs
- Acute lethal dose and reproduction development toxicity screening - Dr. JRK’s 777 oil does not cause reproduction and development toxicity, so it is safe to use during pregnancy.
Ref: Uniqueness of Dr. JRK’s 777 oil and how rancidity distorts Wrightia tinctoria-International Journal of Research in Dermatology - 2019
Proven by rancidity test
Rancid oil and rancid oil preparations are harmful to psoriatic skin and are known to cause irritation, scaling, itching and inflammation, also they increase the risk of cancer.
Acid value is an indicator of oil rancidity. If the drug for psoriasis has a high acid value it negatively impacts psoriasis treatment resulting in aggravation of symptoms and elicit flare-ups of symptoms during remission phase
Dr. JRK’s 777 oil has been extensively researched and proved that most of the oils available in the market have high acid value which are much higher than standard value of 7 as given by Bureau of Indian Standards(BIS).
Ref: Rancid Oil: The Hidden Villain of Psoriasis - Researchand Reviews: Journal of Unani, Siddha and Homeopathy - 2015
Clinical trial conducted to evaluate the efficacy of Dr.JRK’s 777 oil in 26 patients with chronic plaque psoriasis for about 12 weeks study at Ram Monohar Lohia Hospital, New Delhi.
Results reveals that Dr. JRK’s777 oil is as effective as Calcipotriol
Ref: Conversion of Phyto-Actives of JRK’s JRK’s 777 Oil Post-Sun Exposure Exhibit Calcipotrial like Activity – A Clinical Comparison at RML Hospital, New Delhi - Journal of Dermatology and Clinical Research – 2022.