Psoriasis is a chronic inflammatory skin disease mediated by T cells (a type of white blood cell) and dendritic cells (cells responsible for the initiation of adaptive immunity).
Inflammatory myeloid Dendritic cells release Interleukin-23 and Interleukin-12 to activate Interleukin-17 producing T cells, T helper type 1 (Th1) cells, and T helper type 22 cells, which produce abundant pro-inflammatory mediators like tumor necrosis factor-alpha (TNF- α), interleukin-6, interleukin-8. These cytokines mediate effects on keratinocytes to amplify psoriatic inflammation.
Psoriasis can be triggered by many factors, including injury and trauma (termed the Koebner effect), infection, and medications.
WHAT THESE PRO-INFLAMMATORY MEDIATORS DO TO YOUR SKIN?
Pro-inflammatory mediators trigger the T cells and release inflammatory responses that cause an inflammatory flare-up of skin and also trigger hyper-keratinization.
In this inflammatory phase, you can be more susceptible to pain due to the soreness and itching in the inflamed areas.
Lipoxygenase, COX-1, and COX-2 are the enzymes that induce pain.
Glycation end products trigger free radical generation, which in turn causes oxidative stress to the cells, leading to chronic inflammation.
HOW TO TREAT?
Introducing Psorolin B-OINTMENT for psoriasis with powerful, scientifically proven benefits for faster relief in the inflammatory phase and scaling stages of psoriasis.
A prolonged remission period can be achieved with Psorolin B by controlling the pre-inflammatory responses and keratinocyte proliferation.
The Psorolin B ointment for psoriasis is scientifically proven to inhibit pro-inflammatory mediators like TNF-α
Interleukin-6, and Interleukin-8 and reduce the elastase and collagenase enzymes, which are responsible for cell proliferation.
Use Psorolin B ointment for psoriasis and get quick relief from the inflammatory phase of psoriasis.