Psoriasis is a chronic inflammatory skin disease mediated by T cells (a type of white blood cell) and dendritic cells (cells responsible for the initiation of adaptive immunity).

Inflammatory myeloid Dendritic cells release Interleukin-23 and Interleukin-12 to activate Interleukin-17 producing T cells, T helper type 1 (Th1) cells, and T helper type 22 cells, which produce abundant pro-inflammatory mediators like tumor necrosis factor-alpha (TNF- α), interleukin-6, interleukin-8. These cytokines mediate effects on keratinocytes to amplify psoriatic inflammation.

Psoriasis can be triggered by many factors, including injury and trauma (termed the Koebner effect), infection, and medications.


Pro-inflammatory mediators trigger the T cells and release inflammatory responses that cause an inflammatory flare-up of skin and also trigger hyper-keratinization.

In this inflammatory phase, you can be more susceptible to pain due to the soreness and itching in the inflamed areas.

Lipoxygenase, COX-1, and COX-2 are the enzymes that induce pain.

Glycation end products trigger free radical generation, which in turn causes oxidative stress to the cells, leading to chronic inflammation.


Introducing Psorolin B-OINTMENT for psoriasis with powerful, scientifically proven benefits for faster relief in the inflammatory phase and scaling stages of psoriasis.

A prolonged remission period can be achieved with Psorolin B by controlling the pre-inflammatory responses and keratinocyte proliferation.

The Psorolin B ointment for psoriasis is scientifically proven to inhibit pro-inflammatory mediators like TNF-α

 Interleukin-6, and Interleukin-8 and reduce the elastase and collagenase enzymes, which are responsible for cell proliferation.

Use Psorolin B ointment for psoriasis and get quick relief from the inflammatory phase of psoriasis.

Leave a Reply

Your email address will not be published. Required fields are marked *